Irk (disambiguation)
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Irk may refer to:
- River Irk, a river in northwest England
- Kirksville Regional Airport, Kirksville, Missouri, United States
- Inward-rectifier potassium ion channel, a class of protein
- Iraqw language, a Cushitic language spoken in Tanzania
- Irk, the fictional homeworld of main character Zim in the animated TV series Invader Zim
- Islamic Republic of Kamistan, a fictional country in season 8 of the TV series 24
- Irk, Diz, a historical Assyrian hamlet in Hakkari, Turkey
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