International Society for Extracellular Vesicles

The International Society for Extracellular Vesicles (ISEV) is an international scientific organization that focuses on the study of extracellular vesicles (EV),[1] including exosomes, microvesicles, oncosomes, and other membrane-bound particles that are released from cells. Established in 2011, the society is a nonprofit organization. It is governed by an executive committee. The current president is Andrew Hill (2016-2018), the founding president was Jan Lötvall (2011-2016). The society publishes the Journal of Extracellular Vesicles.

International Society for Extracellular Vesicles
Founded2011
TypeProfessional organization
FocusExtracellular vesicles, exosomes
Area served
Worldwide
MethodConferences, publications, education
Members
>1000
Key people
Andrew Hill (president)
Jan Lötvall (founding president)
Clotilde Théry (founding secretary general)
Websiteisev.org

Meetings

As part of its mission to promote scientific research and education, the society hosts an annual meeting and educational event as well as numerous workshops on defined EV-related topics. The society also co-sponsors or endorses related events.

Workshops and scientific seminars

ISEV workshops began with a meeting on extracellular RNA (New York City, 2012),[2][3][4] and continue to include one to two meetings per year.

Endorsed or co-sponsored events

The society has directly or indirectly supported EV-related events around the world. These include meetings of the UK, French, and Spanish and Portuguese EV Societies (GEIVEX), a course the European Molecular Biology Laboratory, a Keystone Symposia conference (2016 and 2018),[5] Gordon Research Conferences (2016 and 2018),[6] a Cold Spring Harbor Asia Meeting (2016),[7] and others.

Journal of Extracellular Vesicles and standardization initiatives

To disseminate research in the field, the society established the peer-reviewed open access Journal of Extracellular Vesicles in 2012.[8] The journal was initially published by Co-Action Publishing, but has been published by Taylor & Francis since 2016. In addition to research and review articles, the journal periodically publishes position papers of the society that are meant to advance standardization efforts.[3][4] In 2014, the Executive Board of Directors published a set of minimal information guidelines for publication of EV studies.[9][10] These requirements, known as "MISEV" or "MISEV2014," mirrored similar initiatives in the fields of microarray (MIAME) and proteomics (MIAPE) analysis, among others. In 2017, the society's board announced its intent to update these requirements with community involvement.[11] The "MISEV2018" requirements were published in 2018 by Clotilde Théry and Kenneth Witwer with input from 380 co-authors.[12]

Education

Among the educational initiatives of the society are massive open online courses (MOOCs), launched in 2016. They are available through Coursera[13][14] and co-sponsored by the University of Gothenburg, Pohang University of Science and Technology, and the University of California, Irvine.[15]

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References
  1. "Better living through mitochondrial derived vesicles". MedicalXpress.
  2. "RNA Workshop". Archived from the original on 2014-05-30. Retrieved 2014-04-29.
  3. Witwer, K. W.; Buzás, E.I.; Bemis, L.T.; Bora, A.; Lässer, C.; Lötvall, J.; Nolte-'t Hoen, E.N.; Piper, M.G.; Sivaraman, S.; Skog, J.; Théry, C.; Wauben, M.H.; Hochberg, F. (2013). "Standardization of sample collection, isolation and analysis methods in extracellular vesicle research". Journal of Extracellular Vesicles. 2: 20360. doi:10.3402/jev.v2i0.20360. PMC 3760646. PMID 24009894.
  4. Hill, A.F.; Pegtel, D.M.; Lambertz, U.; Leonardi, T.; O'Driscoll, L.; Pluchino, S.; Ter-Ovanesyan, D.; Nolte-'t Hoen, E.N. (2013). "ISEV position paper: Extracellular vesicle RNA analysis and bioinformatics". Journal of Extracellular Vesicles. 2: 22859. doi:10.3402/jev.v2i0.22859. PMC 3873759. PMID 24376909.
  5. "Scientific Conferences on Biomedical and Life Science Topics". Keystone Symposia.
  6. "2016 Extracellular Vesicles Conference GRC". Gordon Research Conferences.
  7. "CSH Asia 2016 Conference on Biology & Function of Extracellular Vesicles: Exosomes, Microvesicles & Beyond". Cold Spring Harbor Asia.
  8. "Journal information". Journal of Extracellular Vesicles.
  9. Lötvall, J.; Hill, A.F.; Hochberg, F.; Buzás, E.I.; Di Vizio, D.; Gardiner, C.; Gho, Y.S.; Kurochkin, I.V.; Mathivanan, S.; Quesenberry, P.; Sahoo, S.; Tahara, H.; Wauben, M.H.; Witwer, K.W.; Théry, C. (2014). "Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the International Society for Extracellular Vesicles". Journal of Extracellular Vesicles. 3: 26913. doi:10.3402/jev.v3.26913. PMC 4275645. PMID 25536934.
  10. "Enhanced Analysis of Extracellular Vesicles with Imaging Flow Cytometry". Archived from the original on 2015-12-08. Retrieved 2015-11-28.
  11. Witwer, Kenneth W.; Soekmadji, Carolina; Hill, Andrew F.; Wauben, Marca H.; Buzás, Edit I.; Di Vizio, Dolores; Falcon-Perez, Juan M.; Gardiner, Chris; Hochberg, Fred; Kurochkin, Igor V.; Lötvall, Jan; Mathivanan, Suresh; Nieuwland, Rienk; Sahoo, Susmita; Tahara, Hidetoshi; Torrecilhas, Ana Claudia; Weaver, Alissa M.; Yin, Hang; Zheng, Lei; Gho, Yong Song; Quesenberry, Peter; Théry, Clotilde (2017). "Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility". Journal of Extracellular Vesicles. 6 (1): 1396823. doi:10.1080/20013078.2017.1396823. ISSN 2001-3078. PMC 5698937. PMID 29184626.
  12. Théry, C. (2018). "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines". Journal of Extracellular Vesicles. 7 (1): 1535750. doi:10.1080/20013078.2018.1535750. PMC 6322352. PMID 30637094.
  13. "Basics of Extracellular Vesicles". Coursera.
  14. "Extracellular Vesicles in Health and Disease".
  15. "Well-Attended Two-Track Education Day Precedes Opening of International Society for Extracellular Vesicles (ISEV 2016) Annual Meeting in Rotterdam May 4-7". BioQuick News.com (Press release).
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