Intelectin-2

Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.[3]

ITLN2
Identifiers
Aliases	ITLN2, HL-2, HL2, intelectin 2
External IDs	OMIM: 609874 HomoloGene: 135852 GeneCards: ITLN2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.3 Start 160,945,025 bp[1] End 160,954,809 bp[1]
Orthologs
Species	Human	Mouse
Entrez	142683	n/a
Ensembl	ENSG00000158764	n/a
UniProt	Q8WWU7	n/a
RefSeq (mRNA)	NM_080878	n/a
RefSeq (protein)	NP_543154	n/a
Location (UCSC)	Chr 1: 160.95 – 160.95 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.[4]

See also

• Intelectin

References

1. GRCh38: Ensembl release 89: ENSG00000158764 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Intelectin 2". Retrieved 2016-02-25.
4. Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT (March 2016). "Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition". The Journal of Biological Chemistry. 291 (11): 5596–610. doi:10.1074/jbc.M115.709212. PMC 4786701. PMID 26755729.