Indian childhood cirrhosis

Indian childhood cirrhosis is a chronic liver disease of childhood characterised by cirrhosis of the liver[1] due to deposition of copper in the liver.[2] It primarily affects children of 1–3 years of age and has a genetic predisposition. It had a very high case fatality in the past[3] but has eventually become preventable, treatable and is now rare.[4]

Variants
  • North American Indian childhood cirrhosis [5]
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References
  1. Editorial (August 2008). "Indian childhood cirrhosis: Several dilemmas resolved" (PDF). Indian J Med Res. 128: 93–96. PMID 19001668.
  2. Tanner, MS (May 1998). "Role of copper in Indian childhood cirrhosis". The American Journal of Clinical Nutrition. 67 (5 Suppl): 1074S–1081S. doi:10.1093/ajcn/67.5.1074S. PMID 9587155.
  3. Nayak, NC; et al. "Indian childhood cirrhosis-A reevaluation of its pathognomonic features and their significance in the light of clinical data and natural history of the disease" (PDF). Cite journal requires |journal= (help)
  4. Pandit, A; Bhave, S (May 1996). "Present interpretation of the role of copper in Indian childhood cirrhosis". The American Journal of Clinical Nutrition. 63 (5): 830S–5S. doi:10.1093/ajcn/63.5.830. PMID 8615370.
  5. Richter, A; Mitchell, GA; Rasquin, A (Nov 2007). "[North American Indian childhood cirrhosis (NAIC)]". Médecine/Sciences. 23 (11): 1002–7. doi:10.1051/medsci/200723111002. PMID 18021715.

Further reading
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