Immunoadsorption

Immunoadsorption is an alternative blood purification technique[1] used to eliminate pathogenic antibodies.[2][3][4]

It may be used as an alternative to plasma exchange in certain conditions.[5] Evidence of benefit is lacking in those with kidney problems.[6] Concerns include that it is expensive.[6]

References
  1. Koziolek, Michael J; Tampe, Desiree; Bähr, Matthias; Dihazi, Hassan; Jung, Klaus; Fitzner, Dirk; Klingel, Reinhard; Müller, Gerhard A; Kitze, Bernd (2012). "Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis". Journal of Neuroinflammation. 9: 80. doi:10.1186/1742-2094-9-80. PMC 3418188. PMID 22537481.
  2. Ikeda, Uichi; Kasai, Hiroki; Izawa, Atsushi; Koyama, Jun; Yazaki, Yoshikazu; Takahashi, Masafumi; Higuchi, Makoto; Koh, Chang-Sung; Yamamoto, Keiji (2008). "Immunoadsorption Therapy for Patients with Dilated Cardiomyopathy and Heart Failure". Current Cardiology Reviews. 4 (3): 219–22. doi:10.2174/157340308785160534. PMC 2780823. PMID 19936198.
  3. Hohenstein, B.; Bornstein, S.R.; Aringer, M. (2013). "Immunoadsorption for connective tissue disease". Atherosclerosis Supplements. 14 (1): 185–9. doi:10.1016/j.atherosclerosissup.2012.10.034. PMID 23357163.
  4. Terman, Davids.; Buffaloe, George; Cook, Gary; Sullivan, Michael; Mattioli, Carlos; Tillquist, Richard; Carlos Ayus, Juan (1979). "Extracorporeal Immunoadsorption: Initial Experience in Human Systemic Lupus Erythematosus". The Lancet. 314 (8147): 824. doi:10.1016/S0140-6736(79)92177-9.
  5. Kronbichler, A; Brezina, B; Quintana, LF; Jayne, DR (January 2016). "Efficacy of plasma exchange and immunoadsorption in systemic lupus erythematosus and antiphospholipid syndrome: A systematic review". Autoimmunity Reviews. 15 (1): 38–49. doi:10.1016/j.autrev.2015.08.010. PMID 26318215.
  6. Stummvoll, G; Aringer, M; Handisurya, A; Derfler, K (September 2017). "Immunoadsorption in Autoimmune Diseases Affecting the Kidney". Seminars in Nephrology. 37 (5): 478–487. doi:10.1016/j.semnephrol.2017.05.020. PMID 28863794.


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