IPO11

Importin-11 is a protein that in humans is encoded by the IPO11 gene.[5]

IPO11
Identifiers
Aliases	IPO11, RanBP11, importin 11
External IDs	OMIM: 610889 MGI: 2442377 HomoloGene: 7089 GeneCards: IPO11
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q12.1 Start 62,403,972 bp[1] End 62,628,582 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 D2.1 Start 106,794,439 bp[2] End 106,936,958 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding • Ran GTPase binding • nuclear import signal receptor activity Cellular component • cytoplasm • fibrillar center • cell nucleus • nuclear envelope • cytosol Biological process • protein transport • intracellular protein transport • ribosomal protein import into nucleus • protein import into nucleus Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51194	76582
Ensembl	ENSG00000086200	ENSMUSG00000042590
UniProt	Q9UI26	Q8K2V6
RefSeq (mRNA)	NM_016338 NM_001134779	NM_029665 NM_001360897 NM_175202
RefSeq (protein)	NP_001128251 NP_057422	NP_083941 NP_001347826
Location (UCSC)	Chr 5: 62.4 – 62.63 Mb	Chr 13: 106.79 – 106.94 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000086200 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042590 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: IPO11 importin 11".

Further reading

• Plafker SM, Macara IG (2000). "Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2". EMBO J. 19 (20): 5502–13. doi:10.1093/emboj/19.20.5502. PMC 314000. PMID 11032817.
• Plafker SM, Macara IG (2002). "Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11". Mol. Cell. Biol. 22 (4): 1266–75. doi:10.1128/MCB.22.4.1266-1275.2002. PMC 134630. PMID 11809816.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang W, Yang Y, Li L, Shi Y (2003). "Synleurin, a novel leucine-rich repeat protein that increases the intensity of pleiotropic cytokine responses". Biochem. Biophys. Res. Commun. 305 (4): 981–8. doi:10.1016/S0006-291X(03)00876-3. PMID 12767927.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.