INSL5

Insulin-like peptide INSL5 is a protein that in humans is encoded by the INSL5 gene.[5][6]

INSL5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesINSL5, PRO182, UNQ156, insulin like 5
External IDsOMIM: 606413 MGI: 1346085 HomoloGene: 48350 GeneCards: INSL5
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p31.3Start66,797,741 bp[1]
End66,801,256 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10022

23919

Ensembl

ENSG00000172410

ENSMUSG00000066090

UniProt

Q9Y5Q6

Q9WUG6

RefSeq (mRNA)

NM_005478

NM_001290648
NM_011831

RefSeq (protein)

NP_005469

NP_001277577
NP_035961

Location (UCSC)Chr 1: 66.8 – 66.8 MbChr 4: 103.02 – 103.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7).[6]

gollark: Done.
gollark: https://pastebin.com/Frv3xkB9Full badly-commented thing.
gollark: I *did* test this, you know.
gollark: ```lua-- Convert path to canonical formlocal function canonicalize(path) return fs.combine(path, "")endlocal function path_in(p, dir) return starts_with(canonicalize(p), canonicalize(dir))end-- Resolve a path with the given root - if you go outside it, loops you back inlocal function resolve_path(path, root) if path_in(path, "/rom") then -- allow access to shared ROM return path end local new_path = fs.combine(root, path) if not path_in(new_path, root) then return resolve_path(new_path, root) else return new_path endend```Relevant code.
gollark: FS overrides can create some really "fun" filesystem messes.

References
  1. GRCh38: Ensembl release 89: ENSG00000172410 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000066090 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Conklin D, Lofton-Day CE, Haldeman BA, Ching A, Whitmore TE, Lok S, Jaspers S (August 1999). "Identification of INSL5, a new member of the insulin superfamily". Genomics. 60 (1): 50–6. doi:10.1006/geno.1999.5899. PMID 10458910.
  6. "Entrez Gene: INSL5 insulin-like 5".

Further reading
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