IMP4

U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene.[4][5][6]

IMP4
Identifiers
Aliases	IMP4, BXDC4, IMP4 homolog, U3 small nucleolar ribonucleoprotein, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 4
External IDs	OMIM: 612981 MGI: 106572 HomoloGene: 68891 GeneCards: IMP4
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q21.1 Start 130,342,877 bp[1] End 130,347,967 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • rRNA primary transcript binding • snoRNA binding Cellular component • small-subunit processome • nucleolus • cell nucleus • nucleoplasm • fibrillar center • preribosome • Mpp10 complex Biological process • ribosome biogenesis • rRNA processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	92856	27993
Ensembl	ENSG00000136718	n/a
UniProt	Q96G21	Q8VHZ7
RefSeq (mRNA)	NM_033416 NM_001320304 NM_001320305 NM_001320306 NM_001320307 NM_001320309 NM_001320310 NM_001320311 NM_001371725 NM_001371726 NM_001371728 NM_001371730 NM_001371731 NM_001371732 NM_001371733 NM_001371734	NM_178601
RefSeq (protein)	NP_001307233 NP_001307234 NP_001307235 NP_001307236 NP_001307238 NP_001307239 NP_001307240 NP_219484 NP_001358654 NP_001358655 NP_001358657 NP_001358659 NP_001358660 NP_001358661 NP_001358662 NP_001358663	NP_848716
Location (UCSC)	Chr 2: 130.34 – 130.35 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000136718 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
5. Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
6. "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

Further reading

• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Granneman S, Gallagher JE, Vogelzangs J, et al. (2003). "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes". Nucleic Acids Res. 31 (7): 1877–87. doi:10.1093/nar/gkg300. PMC 152815. PMID 12655004.
• Leary DJ, Terns MP, Huang S (2004). "Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function". Mol. Biol. Cell. 15 (1): 281–93. doi:10.1091/mbc.E03-06-0363. PMC 307547. PMID 14565981.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.