Hygrine

Hygrine is a pyrrolidine alkaloid, found mainly in coca leaves (0.2%). It was first isolated by Carl Liebermann in 1889 (along with a related compound cuscohygrine) as an alkaloid accompanying cocaine in coca. Hygrine is extracted as a thick yellow oil, having a pungent taste and odor.

Hygrine

Names
IUPAC name (R)-1-(1-Methylpyrrolidin-2-yl)-propan-2-one
Identifiers
CAS Number	496-49-1^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:46750^Y
ChemSpider	389762^Y
ECHA InfoCard	100.007.112
KEGG	C06179^Y
PubChem CID	440933
UNII	49H1LNM62X^Y
CompTox Dashboard (EPA)	DTXSID40894081
InChI InChI=1S/C8H15NO/c1-7(10)6-8-4-3-5-9(8)2/h8H,3-6H2,1-2H3/t8-/m1/s1^Y Key: ADKXZIOQKHHDNQ-MRVPVSSYSA-N^Y InChI=1/C8H15NO/c1-7(10)6-8-4-3-5-9(8)2/h8H,3-6H2,1-2H3/t8-/m1/s1 Key: ADKXZIOQKHHDNQ-MRVPVSSYBT
SMILES CC(=O)C[C@H]1CCCN1C
Properties
Chemical formula	C8H15NO
Molar mass	141.21 g/mol
Boiling point	193 to 195 °C (379 to 383 °F; 466 to 468 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is ^YN ?)
Infobox references

See also

• Coca alkaloids

References

• Dr. Ame Pictet (1904). The Vegetable Alkaloids. With particular reference to their chemical constitution. London: Chapman & Hall.
• "Hygrine". Webster's Revised Unabridged Dictionary (? ed.). 1913.
• "USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. National Germplasm Resources Laboratory, Beltsville, Maryland". Archived from the original on December 11, 2012. Retrieved July 15, 2005.