Homolycorine
Homolycorine is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus).
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Names | |
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IUPAC name
(5aR,11bS,11cS)-9,10-Dimethoxy-1-methyl-2,3,5,5a,11b,11c-hexahydroisochromeno[3,4-g]indol-7-one | |
Other names
9,10-Dimethoxy-1-methyllycorenan-7-one | |
Identifiers | |
3D model (JSmol) |
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CompTox Dashboard (EPA) |
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Properties | |
C18H21NO4 | |
Molar mass | 315.369 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Infobox references | |
Sources
- Four new Amaryllidaceae alkaloids from Zephyranthes candida. Shitara N, Hirasawa Y, Hasumi S, Sasaki T, Matsumoto M, Wong CP, Kaneda T, Asakawa Y, Morita H (2014 Jul) Journal of natural medicines, 68(3):610-4
- Acta Crystallographica
- T. Kitagawa, W. I. Taylor, S. Uyeo and H. Yajima. The constitution of homolycorine and lycorenine J. Chem. Soc., 1955, 1066-1068 DOI: 10.1039/JR9550001066
- Bastida, Jaume, Rodolfo Lavilla, and Francesc Viladomat. "CHEMICAL AND BIOLOGICAL ASPECTS OF Narcissus ALKALOIDS", in “The Alkaloids: Chemistry and Biology” (G. A. Cordell, ed.), Vol. 63 pp. 87-179 (2006). Elsevier Inc. Amsterdam. DOI: 10.1016/S1099-4831(06)63003-4
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