Hippocalcin-like protein 4
Hippocalcin like 4, also known as HPCAL4, is a human gene.[5]
HPCAL4 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | HPCAL4, HLP4, hippocalcin like 4 | ||||||||||||||||||||||||
External IDs | MGI: 2157521 HomoloGene: 9441 GeneCards: HPCAL4 | ||||||||||||||||||||||||
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Species | Human | Mouse | |||||||||||||||||||||||
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Location (UCSC) | Chr 1: 39.68 – 39.69 Mb | Chr 4: 123.18 – 123.19 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
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Function
The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. It is a member of the neuronal calcium sensor family.[6] This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites.[5]
gollark: And the Arch one and probably other distros', it's not going to vanish from anywhere else.
gollark: Those websites probably use youtube-dl anyway.
gollark: That's only specified for IPv4.
gollark: Side channels are where instead of looking at the obvious inputs/outputs of a system you look at other information which might be affected by what it's doing, like a chip's power draw, electromagnetic radiation from it, or timing.
gollark: There's some weirdness where it's not *strictly* rolled back entirely so some information can be extracted through bizarre side channels.
References
- GRCh38: Ensembl release 89: ENSG00000116983 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000046093 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: HPCAL4 hippocalcin like 4".
- Burgoyne RD (March 2007). "Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling". Nature Reviews. Neuroscience. 8 (3): 182–93. doi:10.1038/nrn2093. PMC 1887812. PMID 17311005.
Further reading
- Kobayashi M, Sakai E, Furuta Y, Takamatsu K (1999). "Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes". DNA Sequence. 9 (3): 171–6. doi:10.3109/10425179809072192. PMID 10520747.
- Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
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