HAUS3

HAUS augmin-like complex subunit 3 is a protein that in humans is encoded by the HAUS3 gene.[5][6]

HAUS3
Identifiers
Aliases	HAUS3, C4orf15, IT1, dgt3, HAUS augmin like complex subunit 3
External IDs	OMIM: 613430 MGI: 2387633 HomoloGene: 75209 GeneCards: HAUS3
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p16.3 Start 2,078,998 bp[1] End 2,242,276 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 B2|5 17.84 cM Start 34,153,880 bp[2] End 34,169,527 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding • molecular function Cellular component • microtubule cytoskeleton • cytoplasm • microtubule organizing center • centrosome • microtubule • HAUS complex • cytoskeleton • mitochondrion • nucleoplasm • cytosol • spindle • intercellular bridge • mitotic spindle Biological process • spindle assembly • cell cycle • cell division • G2/M transition of mitotic cell cycle • ciliary basal body docking • centrosome cycle • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79441	231123
Ensembl	ENSG00000214367	ENSMUSG00000079555
UniProt	Q68CZ6	Q8QZX2
RefSeq (mRNA)	NM_024511 NM_001303143	NM_146159
RefSeq (protein)	NP_001290072 NP_078787	NP_666271
Location (UCSC)	Chr 4: 2.08 – 2.24 Mb	Chr 5: 34.15 – 34.17 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000214367 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000079555 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: HAUS augmin-like complex".
6. Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr. Biol. 19 (10): 816–26. doi:10.1016/j.cub.2009.04.033. PMID 19427217.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Uehara R, Nozawa RS, Tomioka A, et al. (2009). "The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells". Proc. Natl. Acad. Sci. U.S.A. 106 (17): 6998–7003. doi:10.1073/pnas.0901587106. PMC 2668966. PMID 19369198.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.