HAUS1

HAUS augmin-like complex subunit 1 is a protein that in humans is encoded by the HAUS1 gene.[5][6][7]

HAUS1
Identifiers
Aliases	HAUS1, CCDC5, HEI-C, HEIC, HsT1461, HAUS augmin like complex subunit 1
External IDs	OMIM: 608775 MGI: 2385076 HomoloGene: 15516 GeneCards: HAUS1
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q21.1 Start 46,104,378 bp[1] End 46,128,333 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 E3 Start 77,757,567 bp[2] End 77,767,780 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding • molecular function Cellular component • microtubule organizing center • centrosome • spindle • spindle pole • microtubule • HAUS complex • cytoskeleton • cytoplasm • cytosol Biological process • spindle assembly • cell cycle • cell division • G2/M transition of mitotic cell cycle • ciliary basal body docking • centrosome cycle • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115106	225745
Ensembl	ENSG00000152240	ENSMUSG00000041840
UniProt	Q96CS2	Q8BHX1
RefSeq (mRNA)	NM_138443	NM_146089 NM_001357531 NM_001357532 NM_001357533
RefSeq (protein)	NP_612452	NP_666201 NP_001344460 NP_001344461 NP_001344462
Location (UCSC)	Chr 18: 46.1 – 46.13 Mb	Chr 18: 77.76 – 77.77 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000152240 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000041840 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr Biol. 19 (10): 816–26. doi:10.1016/j.cub.2009.04.033. PMID 19427217.
7. "Entrez Gene: CCDC5 coiled-coil domain containing 5 (spindle associated)".

External links

• Human HAUS1 genome location and HAUS1 gene details page in the UCSC Genome Browser.

Further reading

• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Einarson MB, Cukierman E, Compton DA, Golemis EA (2004). "Human Enhancer of Invasion-Cluster, a Coiled-Coil Protein Required for Passage through Mitosis". Mol. Cell. Biol. 24 (9): 3957–71. doi:10.1128/MCB.24.9.3957-3971.2004. PMC 387757. PMID 15082789.
• Ramachandran N, Hainsworth E, Bhullar B, et al. (2004). "Self-assembling protein microarrays". Science. 305 (5680): 86–90. doi:10.1126/science.1097639. PMID 15232106.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.