Gp100:209-217(210M)

Gp100:209-217(210M) is a synthetic peptide cancer vaccine consisting of amino acid residues 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen, with a methionine substitution at position 210.[1] It is often referred to as the gp100 cancer vaccine which can also include other peptides based on gp100 (for example gp100:280-288(288V) [2][3]).

Clinical trials

It gave good results in a trial for advanced melanoma when used in combination with interleukin-2.[4]

Another trial against Ipilimumab in advanced melanoma suggested Ipilimumab may be better than the gp100 vaccine alone.[5]

gollark: Then you are not an idiot. You win a melon! 🍈
gollark: Anyone who disagrees with me is always an idiot.
gollark: It seems kind of hypocritical of you to simultaneously go "destroy the existing regime violently" and "we need a new form of government which will deal with this sort of thing very harshly and not really allow change".
gollark: Isn't a violent protest or whatever the sort of thing the authoritarian regimes you like try to stop/deal with very harshly?
gollark: So the general principle is "only obey governments I like"?

References
  1. http://www.cancer.gov/drugdictionary/?CdrID=476335
  2. http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=492712
  3. "Re-induction with ipilimumab, gp100 peptide vaccine, or a combination of both from a phase III, randomized, double-blind, multicenter study of previously treated patients with unresectable stage III or IV melanoma". 2010.
  4. "Vaccine shows promise in advanced melanoma -study". Reuters. 30 May 2009.
  5. http://www.genengnews.com/gen-news-highlights/bms-ipilimumab-proves-itself-in-metastatic-melanoma-patients/81243496/


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