Galactose mutarotase

Galactose mutarotase (aldose 1-epimerase) (gene name GALM) is a human enzyme that converts alpha-aldose to the beta-anomer. It belongs to family of aldose epimerases.

GALM
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1SNZ, 1SO0
Identifiers
Aliases	GALM, BLOCK25, GLAT, HEL-S-63p, IBD1, galactose mutarotase (aldose 1-epimerase), galactose mutarotase, GALAC4
External IDs	OMIM: 137030 MGI: 2442420 HomoloGene: 71795 GeneCards: GALM
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p22.1 Start 38,666,081 bp[1] End 38,741,237 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 E3 Start 80,127,471 bp[2] End 80,185,101 bp[2]
Gene ontology Molecular function • isomerase activity • aldose 1-epimerase activity • carbohydrate binding • catalytic activity Cellular component • extracellular exosome • cytoplasm Biological process • hexose metabolic process • glucose metabolic process • galactose metabolic process • galactose catabolic process via UDP-galactose • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	130589	319625
Ensembl	ENSG00000143891	ENSMUSG00000035473
UniProt	Q96C23	Q8K157
RefSeq (mRNA)	NM_138801	NM_176963
RefSeq (protein)	NP_620156	NP_795937
Location (UCSC)	Chr 2: 38.67 – 38.74 Mb	Chr 17: 80.13 – 80.19 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Aldose 1-epimerase (Galactose mutarotase)

1. GRCh38: Ensembl release 89: ENSG00000143891 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035473 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.