Gasdermin A

Gasdermin A is a protein that in humans is encoded by the GSDMA gene. [5]

GSDMA
Identifiers
Aliases	GSDMA, GSDM, GSDM1, FKSG9, gasdermin A
External IDs	OMIM: 611218 MGI: 1889509 HomoloGene: 10962 GeneCards: GSDMA
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.1 Start 39,953,263 bp[1] End 39,977,768 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 98,664,351 bp[2] End 98,677,708 bp[2]
Gene ontology Molecular function • phosphatidylserine binding • phosphatidylinositol-4,5-bisphosphate binding • phosphatidylinositol-4-phosphate binding Cellular component • cytoplasm • perinuclear region of cytoplasm • cytosol • cell membrane • membrane Biological process • programmed cell death • apoptotic process • pyroptosis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	284110	57911
Ensembl	ENSG00000167914	ENSMUSG00000017204
UniProt	Q96QA5	Q9EST1
RefSeq (mRNA)	NM_178171	NM_021347
RefSeq (protein)	NP_835465	NP_067322
Location (UCSC)	Chr 17: 39.95 – 39.98 Mb	Chr 11: 98.66 – 98.68 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000167914 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000017204 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Gasdermin A". Retrieved 2016-08-26.

Further reading

• Katoh M, Katoh M (2004). "Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". Int. J. Oncol. 24 (4): 757–63. doi:10.3892/ijo.24.4.757. PMID 15010812.