Furanochromone

Furanochromone is a chemical compound which is a derivative of chromone (1,4-benzopyrone) and furan.[1]

Furanochromone

Names
IUPAC name 5H-Furo[3,2-g]chromen-5-one
Identifiers
CAS Number	67777-61-1^Y
3D model (JSmol)	Interactive image
ChemSpider	114232
PubChem CID	128913
CompTox Dashboard (EPA)	DTXSID30987113
InChI InChI=1S/C11H6O3/c12-9-2-4-14-11-6-10-7(1-3-13-10)5-8(9)11/h1-6H Key: QBCCGEPNFFWJOU-UHFFFAOYSA-N InChI=1/C11H6O3/c12-9-2-4-14-11-6-10-7(1-3-13-10)5-8(9)11/h1-6H Key: QBCCGEPNFFWJOU-UHFFFAOYAV
SMILES O=C\1c3c(O/C=C/1)cc2occc2c3
Properties
Chemical formula	C11H6O3
Molar mass	186.166 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Some chemical derivatives of furanochromone show strong interaction with DNA.[2] Furanochromones can be produced in callus cultures of Ammi visnaga[3] or in Pimpinella monoica.[4]

References

1. Pereira, David M.; Valentão, Patrícia; Pereira, José A.; Andrade, Paula B. (2009). "Phenolics: From Chemistry to Biology". Molecules. 14 (6): 2202. doi:10.3390/molecules14062202.
2. Niccolai, Neri; Bovalini, Lucia; Martelli, Paola (1986). "The mechanisms of interaction between furanochromones and dna". Biophysical Chemistry. 24 (3): 217–20. doi:10.1016/0301-4622(86)85027-X. PMID 3768467.
3. Krolicka A.; Staniszewska I.; Malinski E.; Szafranek J.; Łojkowska E. (2003). "Stimulation of furanochromone accumulation in callus cultures of Ammi visnaga L. by addition of elicitors". Pharmazie. 58 (8): 590–592. PMID 12967041.
4. Luthria, D.L.; Banerji, A. (1994). "Biosynthesis of furanochromones in Pimpinella monoica" (PDF). Proceedings of the Indian Academy of Sciences – Chemical Sciences. 106 (5): 1149–1156. doi:10.1007/BF02841922 (inactive 2020-05-21).