Follicular hyperplasia

Follicular hyperplasia is a type of lymphoid hyperplasia. It is caused by a stimulation of the B cell compartment.[1] It is caused by an abnormal proliferation of secondary follicles and occurs principally in the cortex without broaching the lymph node capsule. The follicles are cytologically polymorphous, are often polarized, and vary in size and shape.[2] Follicular hyperplasia is distinguished from follicular lymphoma in its polyclonality and lack of bcl-2 protein expression, whereas follicular lymphoma is monoclonal, and does express bcl-2[3]).

Follicular hyperplasia
Other namesReactive follicular hyperplasia, Lymphoid nodular hyperplasia

Causes

Some specific reactive lymphadenopathies with a predominantly follicular pattern:[4]

Diagnosis

Treatment
gollark: Pascal's Wager basically goes "if no god, belief doesn't have costs anyway (wrong, since it takes time and may make your thinking more irrational); if god, non-belief means infinite badness (hell), belief means infinite goodness (heaven), so rationally you should believe".
gollark: There *may* be a god of some kind who rewards you for believing in them and their afterlife and such, but there is an infinity of possible gods including ones like "allocates you to heaven or hell entirely at random", "entirely indistinguishable from no god", "sends you to hell if you believe in the *other* god", "incomprehensible eldritch abomination" or "literal bees".
gollark: PASACL'S WAGER BAD
gollark: ÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆÆA
gollark: Whether there *is*... some supernatural thing after death, such as an afterlife... is pretty much independent of whether you believe it or not, and while the exact form of that *may* depend on your beliefs about it, that makes a LOT of presumptions about god or who/what created the system which are not supported.

References
  1. Weiss, L. M.; O'Malley, D (2013). "Benign lymphadenopathies". Modern Pathology. 26 Suppl 1: S88–96. doi:10.1038/modpathol.2012.176. PMID 23281438.
  2. Drew, Torigan; et al. (2001). "Lymphoid hyperplasia of stomach". American Journal of Roentgenology. 177 (1): 71–75. doi:10.2214/ajr.177.1.1770071. PMID 11418401.
  3. Sattar, Husain (2016). Fundamentals of Pathology. Chicago. ISBN 9780983224624.
  4. Weiss, L. M.; O'Malley, D (2013). "Benign lymphadenopathies". Modern Pathology. 26 Suppl 1: S88–96. doi:10.1038/modpathol.2012.176. PMID 23281438.
  5. John H. Stone; Arezou Khosroshahi; Vikram Deshpande; et al. (October 2012). "Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations". Arthritis & Rheumatism. 64 (10): 3061–3067. doi:10.1002/art.34593. PMC 5963880. PMID 22736240.


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