Fat atypical cadherin 3

FAT atypical cadherin 3 is a protein that in humans is encoded by the FAT3 gene.[5]

FAT3
Identifiers
Aliases	FAT3, CDHF15, CDHR10, hFat3, FAT atypical cadherin 3
External IDs	OMIM: 612483 MGI: 2444314 HomoloGene: 82252 GeneCards: FAT3
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.3 Start 92,352,096 bp[1] End 92,896,470 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A2 Start 15,910,189 bp[2] End 16,501,285 bp[2]
Gene ontology Molecular function • calcium ion binding Cellular component • integral component of membrane • cell membrane • membrane Biological process • homophilic cell adhesion via plasma membrane adhesion molecules • multicellular organism development • cell adhesion • cell-cell adhesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	120114	270120
Ensembl	ENSG00000165323	ENSMUSG00000074505
UniProt	Q8TDW7	Q8BNA6
RefSeq (mRNA)	NM_001008781 NM_001367949 NM_001378141	NM_001080814
RefSeq (protein)	NP_001008781 NP_001354878 NP_001365070	NP_001074283
Location (UCSC)	Chr 11: 92.35 – 92.9 Mb	Chr 9: 15.91 – 16.5 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000165323 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000074505 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: FAT atypical cadherin 3".

Further reading

• Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT (September 2011). "Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling". The Journal of Cell Biology. 194 (5): 737–50. doi:10.1083/jcb.201107021. PMC 3171123. PMID 21875946.
• Zheng JS, Arnett DK, Lee YC, Shen J, Parnell LD, Smith CE, Richardson K, Li D, Borecki IB, Ordovás JM, Lai CQ (2013). "Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits". PLOS One. 8 (10): e77442. doi:10.1371/journal.pone.0077442. PMC 3810463. PMID 24204828.
• Mitsui K, Nakajima D, Ohara O, Nakayama M (February 2002). "Mammalian fat3: a large protein that contains multiple cadherin and EGF-like motifs". Biochemical and Biophysical Research Communications. 290 (4): 1260–6. doi:10.1006/bbrc.2002.6338. PMID 11811999.
• Wu Q (April 2005). "Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes". Genetics. 169 (4): 2179–88. doi:10.1534/genetics.104.037606. PMC 1449604. PMID 15744052.