FSCN3

Fascin-3 also known as testis fascin is a protein that in humans is encoded by the FSCN3 gene.[5][6]

FSCN3
Identifiers
Aliases	FSCN3, fascin actin-bundling protein 3
External IDs	OMIM: 615800 MGI: 1890386 HomoloGene: 10475 GeneCards: FSCN3
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q32.1 Start 127,591,409 bp[1] End 127,602,144 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A3.3 Start 28,427,789 bp[2] End 28,438,622 bp[2]
Gene ontology Molecular function • protein binding, bridging • actin binding • actin filament binding Cellular component • cytoskeleton • actin cytoskeleton • cytoplasm • filamentous actin • ruffle • microvilli • lamellipodium • filopodium • growth cone • cell projection membrane Biological process • spermatid development • actin filament organization • anatomical structure morphogenesis • establishment or maintenance of cell polarity • actin filament bundle assembly • cell migration Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29999	56223
Ensembl	ENSG00000106328	ENSMUSG00000029707
UniProt	Q9NQT6	Q9QXW4
RefSeq (mRNA)	NM_020369	NM_019569
RefSeq (protein)	NP_065102	NP_062515
Location (UCSC)	Chr 7: 127.59 – 127.6 Mb	Chr 6: 28.43 – 28.44 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Fascin

References

1. GRCh38: Ensembl release 89: ENSG00000106328 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029707 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: fascin homolog 3".
6. Tubb B, Mulholland DJ, Vogl W, Lan ZJ, Niederberger C, Cooney A, Bryan J (April 2002). "Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head". Exp. Cell Res. 275 (1): 92–109. doi:10.1006/excr.2002.5486. PMID 11925108.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Tubb BE, Bardien-Kruger S, Kashork CD, et al. (2000). "Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes". Genomics. 65 (2): 146–56. doi:10.1006/geno.2000.6156. PMID 10783262.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.