FCRL2

Fc receptor-like protein 2 is a protein that in humans is encoded by the FCRL2 gene.[3][4]

FCRL2
Identifiers
Aliases	FCRL2, CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C, Fc receptor like 2
External IDs	OMIM: 606509 HomoloGene: 57121 GeneCards: FCRL2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.1 Start 157,745,733 bp[1] End 157,777,132 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cell membrane • membrane • integral component of membrane • cell surface Biological process • cell-cell signaling • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79368	n/a
Ensembl	ENSG00000132704	n/a
UniProt	Q96LA5	n/a
RefSeq (mRNA)	NM_001159488 NM_030764 NM_138738	n/a
RefSeq (protein)	NP_001152960 NP_110391	n/a
Location (UCSC)	Chr 1: 157.75 – 157.78 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000132704 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Xu MJ, Zhao R, Zhao ZJ (Feb 2001). "Molecular cloning and characterization of SPAP1, an inhibitory receptor". Biochem Biophys Res Commun. 280 (3): 768–75. doi:10.1006/bbrc.2000.4213. PMID 11162587.
4. "Entrez Gene: FCRL2 Fc receptor-like 2".

Further reading

• Davis RS, Wang YH, Kubagawa H, Cooper MD (2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772–7. doi:10.1073/pnas.171308498. PMC 55528. PMID 11493702.
• Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–9. doi:10.1182/blood.V99.8.2662. PMID 11929751.
• Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
• Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–8. doi:10.1007/s00251-007-0195-9. PMID 17273841.