FCRL1

Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene.[5][6][7]

FCRL1
Identifiers
Aliases	FCRL1, CD307a, FCRH1, IFGP1, IRTA5, Fc receptor like 1
External IDs	OMIM: 606508 MGI: 2442862 HomoloGene: 50472 GeneCards: FCRL1
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q23.1 Start 157,794,403 bp[1] End 157,820,120 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 87,376,387 bp[2] End 87,402,934 bp[2]
Gene ontology Molecular function • coreceptor activity Cellular component • membrane • integral component of membrane • cell membrane • cell surface Biological process • signal transduction • B cell activation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115350	229499
Ensembl	ENSG00000163534	ENSMUSG00000059994
UniProt	Q96LA6	Q8R4Y0
RefSeq (mRNA)	NM_001159397 NM_001159398 NM_052938	NM_001136236 NM_153090 NM_178165 NM_001310545
RefSeq (protein)	NP_001152869 NP_001152870 NP_443170	NP_001129708 NP_001297474 NP_694730 NP_835459
Location (UCSC)	Chr 1: 157.79 – 157.82 Mb	Chr 3: 87.38 – 87.4 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163534 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059994 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc Natl Acad Sci U S A. 98 (17): 9772–9777. doi:10.1073/pnas.171308498. PMC 55528. PMID 11493702.
6. Miller I, Hatzivassiliou G, Cattoretti G, Mendelsohn C, Dalla-Favera R (Apr 2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–2669. doi:10.1182/blood.V99.8.2662. PMID 11929751.
7. "Entrez Gene: FCRL1 Fc receptor-like 1".

Further reading

• Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–328. doi:10.1007/s00251-007-0195-9. PMID 17273841.
• Leu CM, Davis RS, Gartland LA, et al. (2005). "FcRH1: an activation coreceptor on human B cells". Blood. 105 (3): 1121–1126. doi:10.1182/blood-2004-06-2344. PMID 15479727.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601.