FBRS

Probable fibrosin-1 long transcript protein is a protein that in humans is encoded by the FBRS gene.[5][6][7]

FBRS
Identifiers
Aliases	FBRS, FBS, FBS1, fibrosin
External IDs	OMIM: 608601 MGI: 104648 HomoloGene: 79554 GeneCards: FBRS
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 30,658,431 bp[1] End 30,670,810 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 127,479,199 bp[2] End 127,491,711 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • growth factor activity Cellular component • extracellular Biological process • positive regulation of fibroblast proliferation • regulation of receptor activity Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64319	14123
Ensembl	ENSG00000156860	ENSMUSG00000042423
UniProt	Q9HAH7	Q8R089
RefSeq (mRNA)	NM_001105079 NM_022452	NM_010183
RefSeq (protein)	NP_001098549	NP_034313
Location (UCSC)	Chr 16: 30.66 – 30.67 Mb	Chr 7: 127.48 – 127.49 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation (Prakash and Robbins, 1998).[supplied by OMIM][7]

References

1. GRCh38: Ensembl release 89: ENSG00000156860 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042423 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Prakash S, Robbins PW, Wyler DJ (Apr 1995). "Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin". Proc Natl Acad Sci U S A. 92 (6): 2154–8. doi:10.1073/pnas.92.6.2154. PMC 42442. PMID 7892239.
6. Prakash S, Robbins PW (Nov 1998). "Cloning and analysis of the cDNA for human fibrosin, a novel fibrogenic lymphokine". DNA Cell Biol. 17 (10): 879–84. doi:10.1089/dna.1998.17.879. PMID 9809749.
7. "Entrez Gene: FBS1 fibrosin 1".

Further reading

• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
• Prakash S, Nanji AA, Robbins PW (1999). "Fibrosin: A novel lymphokine in alcohol-induced fibrosis". Exp. Mol. Pathol. 67 (1): 40–9. doi:10.1006/exmp.1999.2274. PMID 10493891.
• Prakash S, Robbins PW (2002). "Fibrosin: a novel lymphokine in wound healing". Exp. Mol. Pathol. 71 (3): 247–55. doi:10.1006/exmp.2001.2402. PMID 11733950.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Prakash S, Paul WE, Robbins PW (2007). "Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts". Exp. Mol. Pathol. 82 (1): 42–8. doi:10.1016/j.yexmp.2006.06.008. PMID 17083929.