Epipodophyllotoxin
Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant (Podophyllum peltatum).
![](../I/m/Etoposide.svg.png)
Etoposide, an epipodophyllotoxin
Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II.[1]
See also
References
- Takimoto CH, Calvo E. "Principles of Oncologic Pharmacotherapy" in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) Cancer Management: A Multidisciplinary Approach. 11 ed. 2008.
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