Ecdysteroid

Ecdysteroids are arthropod steroid hormones that are mainly responsible for molting, development and, to a lesser extent, reproduction;[1][2][3] examples of ecdysteroids include ecdysone, ecdysterone, turkesterone and 2-deoxyecdysone.[4] These compounds are synthesized in arthropods from dietary cholesterol upon metabolism by the Halloween family of cytochrome P450s.[5] Phytoecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects.[6][7]

Chemical structure of the ecdysteroid ecdysone

See also

• Ecdysone receptor

References

1. de Loof A (2006). "Ecdysteroids: the overlooked sex steroids of insects? Males: the black box". Insect Science. 13 (5): 325–338. doi:10.1111/j.1744-7917.2006.00101.x.
2. KRISHNAKUMARAN, A.; SCHNEIDERMAN, H. A. (December 1970). "Control of Molting in Mandibulate and Chelicerate Arthropods by Ecdysones". The Biological Bulletin. 139 (3): 520–538. doi:10.2307/1540371. ISSN 0006-3185. JSTOR 1540371. PMID 5494238.
3. Margam, Venu M.; Gelman, Dale B.; Palli, Subba R. (2006-06-01). "Ecdysteroid titers and developmental expression of ecdysteroid-regulated genes during metamorphosis of the yellow fever mosquito, Aedes aegypti (Diptera: Culicidae)". Journal of Insect Physiology. 52 (6): 558–568. doi:10.1016/j.jinsphys.2006.02.003. ISSN 0022-1910. PMID 16580015.
4. "Ecdysteroids Information". Examine.com. Retrieved 27 May 2015.
5. Mykles, Donald L. (2011-11-01). "Ecdysteroid metabolism in crustaceans". The Journal of Steroid Biochemistry and Molecular Biology. 127 (3–5): 196–203. doi:10.1016/j.jsbmb.2010.09.001. ISSN 0960-0760. PMID 20837145.
6. Dinan L (2001). "Phytoecdysteroids: biological aspects". Phytochemistry. 57 (3): 325–339. doi:10.1016/S0031-9422(01)00078-4. PMID 11393511.
7. Dinan L, Savchenko T, Whiting P (2001). "On the distribution of phytoecdysteroids in plants". Cellular and Molecular Life Sciences. 58 (8): 1121–1132. doi:10.1007/PL00000926. PMID 11529504.