ERC2 (gene)
ERC protein 2 is a protein that in humans is encoded by the ERC2 gene.[5]
Interactions
ERC2 (gene) has been shown to interact with PPFIA4,[6] RIMS1,[7][8] UNC13A,[9] and liprin-alpha-1.[6]
gollark: - I believe we should end racial discrimination by replacing computer monitors with 1-bit black and white displays so race cannot be distinguished.
gollark: - As eating meat places suffering on millions of innocent animals, I believe animal meat should be replaced with human flesh from donors, as humans are able to meaningfully consent to this while animals are not (and don't get a choice in practice anyway).
gollark: - To increase the efficiency of the education system and encourage self-directed learning, I believe schools should lock children in individual cubicles with textbooks for 5 hours a day instead of using classrooms and teachers.
gollark: - It's important to me that women aren't forced to have children they don't want or may not be able to take care of.- which is why I support mandatory sterilization for all - children would be grown in vats and raised by the government instead.
gollark: - I support the right to privacy!- In light of governments' large-scale mass surveillance campaigns which they do not seem inclined to stop, I would support an open and transparent volunteer spying agency using open source software and hardware to gather and process data in order to act as a competitor.
References
- GRCh38: Ensembl release 89: ENSG00000187672 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000040640 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: ERC2 ELKS/RAB6-interacting/CAST family member 2".
- Ko J, Na M, Kim S, Lee JR, Kim E (October 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". The Journal of Biological Chemistry. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
- Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y (January 2004). "Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release". The Journal of Cell Biology. 164 (2): 301–11. doi:10.1083/jcb.200307101. PMC 2172332. PMID 14734538.
- Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y (August 2002). "Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1". The Journal of Cell Biology. 158 (3): 577–90. doi:10.1083/jcb.200202083. PMC 2173811. PMID 12163476.
- "Protein unc-13 homolog A". UniProt.
Further reading
- Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. CiteSeerX 10.1.1.500.923. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (April 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
- Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y (August 2002). "Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1". The Journal of Cell Biology. 158 (3): 577–90. doi:10.1083/jcb.200202083. PMC 2173811. PMID 12163476.
- Wang Y, Liu X, Biederer T, Südhof TC (October 2002). "A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones". Proceedings of the National Academy of Sciences of the United States of America. 99 (22): 14464–9. doi:10.1073/pnas.182532999. PMC 137906. PMID 12391317.
- Ko J, Na M, Kim S, Lee JR, Kim E (October 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". The Journal of Biological Chemistry. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
- Deguchi-Tawarada M, Inoue E, Takao-Rikitsu E, Inoue M, Ohtsuka T, Takai Y (January 2004). "CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST". Genes to Cells. 9 (1): 15–23. doi:10.1111/j.1356-9597.2004.00697.x. PMID 14723704.
- Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y (January 2004). "Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release". The Journal of Cell Biology. 164 (2): 301–11. doi:10.1083/jcb.200307101. PMC 2172332. PMID 14734538.
- tom Dieck S, Altrock WD, Kessels MM, Qualmann B, Regus H, Brauner D, Fejtová A, Bracko O, Gundelfinger ED, Brandstätter JH (February 2005). "Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex". The Journal of Cell Biology. 168 (5): 825–36. doi:10.1083/jcb.200408157. PMC 2171818. PMID 15728193.
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