Propylparaben

Propylparaben
Names
	IUPAC name Propyl 4-hydroxybenzoate
	Other names 4-Hydroxybenzoesäurepropylester; Propyl paraben; Propyl p-hydroxybenzoate; Propyl parahydroxybenzoate; Nipasol; E216;
Identifiers
CAS Number	94-13-3 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:32063;
ChEMBL	ChEMBL194014 ;
ChemSpider	6907 ;
ECHA InfoCard	100.002.098
EC Number	202-307-7;
E number	E216 (preservatives)
KEGG	D01422 ;
PubChem CID	7175;
UNII	Z8IX2SC1OH ;
CompTox Dashboard (EPA)	DTXSID4022527 ;
	InChI InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3 Key: QELSKZZBTMNZEB-UHFFFAOYSA-N ; InChI=1/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3 Key: QELSKZZBTMNZEB-UHFFFAOYAD;
	SMILES O=C(OCCC)c1ccc(O)cc1;
Properties
Chemical formula	C10H12O3
Molar mass	180.203 g·mol−1
Density	1.0630 g/cm3
Melting point	96 to 99 °C (205 to 210 °F; 369 to 372 K)
Hazards
NFPA 704 (fire diamond)	1 2 0
Related compounds
Related compounds	Paraben; Butylparaben; Ethylparaben; Methylparaben
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Propylparaben, the n-propyl ester of p-hydroxybenzoic acid, occurs as a natural substance found in many plants and some insects, although it is manufactured synthetically for use in cosmetics, pharmaceuticals, and foods.[1] It is a member of the class of parabens. It is a preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos, and bath products. As a food additive, it has the E number E216.

Sodium propyl p-hydroxybenzoate, the sodium salt of propylparaben, a compound with formula Na(C₃H₇(C₆H₄COO)O), is also used similarly as a food additive and as an anti-fungal preservation agent. Its E number is E217.

In 2010 the European Union Scientific Committee on Consumer Safety stated that it considered the use of butylparaben and propylparaben as preservatives in finished cosmetic products as safe to the consumer, as long as the sum of their individual concentrations does not exceed 0.19%.[2]

References

Oishi (2002). "Effects of propyl paraben on the male reproductive system". Food and Chemical Toxicology. 40 (12): 1807–13. doi:10.1016/s0278-6915(02)00204-1. PMID 12419695.
Directorate-General for Consumer Safety, European Union (2011). "Scientific Committee on Consumer Safety Opinion on Parabens COLIPA n° P82" (PDF). Retrieved December 15, 2017.

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[1] Oishi (2002). "Effects of propyl paraben on the male reproductive system". Food and Chemical Toxicology. 40 (12): 1807–13. doi:10.1016/s0278-6915(02)00204-1. PMID 12419695.

[2] Directorate-General for Consumer Safety, European Union (2011). "Scientific Committee on Consumer Safety Opinion on Parabens COLIPA n° P82" (PDF). Retrieved December 15, 2017.