DnaX ribosomal frameshifting element

The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products, tau and gamma, which are produced in a 1:1 ratio. The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are DNA polymerase III subunits.[1][2]

DnaX ribosomal frameshifting element
Predicted secondary structure and sequence conservation of DnaX
Identifiers
SymbolDnaX
RfamRF00382
Other data
RNA typeCis-reg; frameshift_element
Domain(s)Bacteria
SO0005836
PDB structuresPDBe

References

  1. Larsen B, Gesteland RF, Atkins JF (August 1997). "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50%". Journal of Molecular Biology. 271 (1): 47–60. doi:10.1006/jmbi.1997.1162. PMC 7126992. PMID 9300054.
  2. Blinkova A, Burkart MF, Owens TD, Walker JR (July 1997). "Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium". Journal of Bacteriology. 179 (13): 4438–4442. doi:10.1128/jb.179.13.4438-4442.1997. PMC 179275. PMID 9209069.
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