Doravirine/lamivudine/tenofovir
Doravirine/lamivudine/tenofovir (brand name Delstrigo) is a fixed-dose combination drug for the treatment of HIV/AIDS.[1][2] It contains doravirine, lamivudine, and tenofovir disoproxil.[3][2] In the United States, in August 2018, it was approved by the Food and Drug Administration (FDA) for the treatment of HIV-1 infection.[3][4]
Combination of | |
---|---|
Doravirine | Non-nucleoside reverse transcriptase inhibitor |
Lamivudine | Nucleoside reverse transcriptase inhibitor |
Tenofovir disoproxil | Nucleotide reverse transcriptase inhibitor |
Clinical data | |
Trade names | Delstrigo |
Other names | MK-1439A |
AHFS/Drugs.com | Monograph |
MedlinePlus | a618049 |
License data | |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
KEGG |
References
- "Delstrigo- doravirine, lamivudine, and tenofovir disoproxil fumarate tablet, film coated". DailyMed. 10 October 2019. Retrieved 31 July 2020.
- Canadian Agency for Drugs and Technologies in Health (June 2019). "Common Drug Review New Combination Product: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination (Delstrigo)". CADTH Common Drug Reviews. Ottawa (ON). PMID 31393687.
- "FDA Approves Merck's DELSTRIGO (doravirine / lamivudine / tenofovir disoproxil fumarate), a Once-Daily Fixed-Dose Combination Tablet as a Complete Regimen and PIFELTRO (doravirine), an NNRTI, Both for the Treatment of HIV-1 in Appropriate Patients" (Press release). Merck & Co. 30 August 2018.
- "Delstrigo approval letter" (PDF). Food and Drug Administration (FDA). 30 August 2018. Retrieved 10 September 2019.
External links
- "Doravirine". Drug Information Portal. U.S. National Library of Medicine.
- "Lamivudine". Drug Information Portal. U.S. National Library of Medicine.
- "Tenofovir disoproxil". Drug Information Portal. U.S. National Library of Medicine.
- "Tenofovir disoproxil fumarate". Drug Information Portal. U.S. National Library of Medicine.
- "doravirine lamuvidine tenofovir disoproxil fumarate". Canadian Agency for Drugs and Technologies in Health (CADTH).
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