De Sio
De Sio is a surname of Italian origin. It may refer to:
- Denise De Sio (b. 1952), Italian-American Lesbian Community leader
- Giuliana De Sio (b. 1957), Italian actress
- Teresa De Sio (b. 1955), Italian folk singer-songwriter
- Vincenzo De Sio (b. 1972), Italian former football player
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