DIXDC1

Dixin is a protein that in humans is encoded by the DIXDC1 gene.[5][6] When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.[7]

DIXDC1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDIXDC1, CCD1, DIX domain containing 1
External IDsOMIM: 610493 MGI: 2679721 HomoloGene: 82369 GeneCards: DIXDC1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q23.1Start111,927,144 bp[1]
End112,022,653 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

85458

330938

Ensembl

ENSG00000150764

ENSMUSG00000032064

UniProt

Q155Q3

Q80Y83

RefSeq (mRNA)

NM_001037954
NM_001278542
NM_033425

NM_178118
NM_001311069
NM_001374656

RefSeq (protein)

NP_001033043
NP_001265471
NP_219493

NP_001297998
NP_835219
NP_001361585

Location (UCSC)Chr 11: 111.93 – 112.02 MbChr 9: 50.66 – 50.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000150764 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032064 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Katoh M, Katoh M (July 2003). "KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein with myosine-tail homologous domain and C-terminal DIX domain". International Journal of Oncology. 23 (1): 145–50. doi:10.3892/ijo.23.1.145. PMID 12792787.
  6. "Entrez Gene: DIXDC1 DIX domain containing 1".
  7. http://medicalxpress.com/news/2014-07-gene-deadly-cancer.html#nRlv

Further reading

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