Corinna S. Schindler

Corinna S. Schindler is an assistant professor at the University of Michigan, College of Literature, Science and Arts.

Early life and education

Schindler grew up in Germany, where she also did her undergraduate work.[1]

As an undergraduate, Schindler attended the Technical University of Munich (TUM). She completed her diploma thesis (equivalent of a master of science) under the direction of K. C. Nicolaou at the Scripps Research Institute in La Jolla. Schindler earned her doctorate degree at the ETH Zurich under the direction of Erick M. Carreira. Her Ph.D. thesis focused on the development of new synthetic strategies of natural products centered on the opening of oxabicyclic ring systems.  After completing her doctorate degree, Dr. Schindler joined Eric N. Jacobsen’s research group at Harvard University as a Feodor Lynen Postdoctoral Fellow.[2]

Research interests

Schindler’s research group includes an international team of researchers working in the area of organic chemistry with an emphasis on the synthesis of molecules of biological importance.  Key areas of interest include the development of new synthetic routes for molecules that are potentially important in the areas of material science and medicine.   Her laboratory recently has been successful in incorporating a “green” iron catalyst in a carbonyl-olefin ring closure metathesis reaction [3] that can replace the current precious metal reagents, which are expensive and can be harmful to the environment. The catalyst used is iron (III) chloride. A catalyst is a species that speeds up the kinetics of a reaction by lowering its activation energy and is recovered at the end of the reaction. Catalysts are used to improve reaction yields and decrease reaction times. Schindler's research group also focuses on the biological activity of natural products and their analogs for medicinal purposes.[4]

Awards

For her contributions to science, Schindler has been the recipient of many research awards.[5]  These include:

  • Feodor-Lynen Fellowship Alexander von Humboldt Foundation (2010)
  • ETH Medal (2011)
  • NSF CAREER AWARD (2016)
  • Camille Dreyfus Teacher-Scholar Award (2018)
  • C&E News Talented Twelve (2017)
  • Alfred Sloan Foundation Fellow (2107)

Publications (as PI)

  • "Facile Formation of N-Acyl-oxazolidinone Derivatives Using Acid Fluorides.” Schindler, C.S.; Forster, P.M.; Carreira, E.M. Org. Lett. 2010, 12, 4102–4105.
  • "Nucleophilic Ring Opening of Oxabicyclic Ring Systems.”  Schindler, C.S.; Diethelm, S.; Carreira, E.M. Angew. Chem. Int. Ed. 2009, 48, 6296–6299.
  • “Rapid Formation of Complexity in the Total Synthesis of Natural Products Enabled by  Oxabicyclo(2.2.1)hep-tane building blocks."Schindler, C.S.; Carreira, E.M. Chem. Soc. Rev. 2009, 38, 3222–3241.
  • "Enantioselective Synthesis of the Core of Bayaside, Suomilide and Spumigin HKVV." Schindler, C.S.; Stephenson, C.R.J.; Carreira, E.M. Angew. Chem. Int. Ed. 2008, 47, 8852–8855.
  • "A New Twist on Cooperative Catalysis”.  Schindler, C.S.; Jacobsen, E.N. Science 2013, 340, 1052–1053.
  • "Total Synthesis of Nominal Banyaside B: Structural Revision of the Glycosylation Site." Schindler, C.S.; Bertschi, L.; Carreira, E.M. Angew. Chem. Int. Ed. 2010, 49, 9229-9232
gollark: We ran your brain in a GTech™ neural imprint debugger, and it turns out you're not actually conscious but just a P-zombie. Sorry about that.
gollark: Idea: encode arbitrary Turing machines in a language grammar. Make people acquire it from birth. ???. Computation. Profit.
gollark: Or maybe our brains' language bits *are* actually hardwired for SVO-ish trees.
gollark: I imagine humans might be able to deal with it if you raised them with stacklangs from birth.
gollark: If you're sure.

References

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