Cold abscess

Cold abscess refers to an abscess that lacks the intense inflammation usually associated with infection. This may be associated with infections due to bacteria like tuberculosis[1] and fungi like blastomycosis[2] that do not tend to stimulate acute inflammation. Alternatively, cold abscesses are typical in persons with hyperimmunoglobulin E syndrome, even when infected with an organism like Staphylococcus aureus that causes abscesses with inflammation in others.[3]

Signs of acute inflammation are absent, so the abscess is not hot and red as in a typical abscess filled with pus. Cold abscesses are generally painless cysts that may be subcutaneous, ocular, or in deep tissue such as the spine.[4][5]

See also
  • Tuberculous cervical lymphadenitis

References
  1. Garg, RK; Somvanshi, DS (2011). "Spinal tuberculosis: A review". The Journal of Spinal Cord Medicine. 34 (5): 440–54. doi:10.1179/2045772311Y.0000000023. PMC 3184481. PMID 22118251.
  2. Ferri, Fred (2015). "Blastomycosis". Ferri's Clinical Advisor. Philadelphia: Mosby (Elsevier). pp. 198.e2–198.e4. ISBN 9780323083751.
  3. Holland, SM; DeLeo, FR; Elloumi, HZ; Hsu, AP; et al. (18 October 2007). "Mutations in the hyper-IgE syndrome". The New England Journal of Medicine. 357 (16): 1608–19. doi:10.1056/NEJMoa073687. PMID 17881745.
  4. Ansari, S; Amanullah, MF; Ahmad, K; Rauniyar, RK (July 2013). "Pott's spine: Diagnostic imaging modalities and technology advancements". North American Journal of Medical Sciences. 5 (7): 404–11. doi:10.4103/1947-2714.115775. PMC 3759066. PMID 24020048.
  5. Madge, SN; Prabhakaran, VC; Shome, D; Kim, U; et al. (2008). "Orbital tuberculosis: A review of the literature". Orbit. Amsterdam, Netherlands. 27 (4): 267–77. doi:10.1080/01676830802225152. PMID 18716964.
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