Clofibric acid

Clofibric acid is a herbicide with the IUPAC name 2-(4-chlorophenoxy)-2-methylpropanoic acid and molecular formula C10H11ClO3. It functions as a plant growth regulator against the plant hormone auxin. Clofibric acid is also a naturally-occurring pharmaceutical compound,[1] having been found in Swiss lakes and the North Sea.[2]

Clofibric acid
Names
Preferred IUPAC name
2-(4-Chlorophenoxy)-2-methylpropanoic acid
Other names
Clofibrin
Chlorofibrinic acid
Chlorophenoxyisobutyric acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.011.751
KEGG
UNII
Properties
C10H11ClO3
Molar mass 214.645 g/mol
Appearance White to yellow solid
Melting point 118 to 123 °C (244 to 253 °F; 391 to 396 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Clofibric acid is a metabolite of the cholesterol-lowering pharmaceutical drug clofibrate, as well as that of the lipid regulators clofibrate, etofibrate, and theofibrate.[1]

Clofibric acid derivatives include etofibrate, pirifibrate, and picafibrate.

See also

References

  1. Packer, Jennifer L; Werner, Jeffrey J; Latch, Douglas E; McNeill, Kristopher; Arnold, William A (2003). "Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen". Aquatic Sciences - Research Across Boundaries. 65 (4): 342–351. doi:10.1007/s00027-003-0671-8.
  2. Buser, Hans-Rudolf; Müller, Markus D; Theobald, Norbert (1998). "Occurrence of the Pharmaceutical Drug Clofibric Acid and the Herbicide Mecoprop in Various Swiss Lakes and in the North Sea". Environmental Science & Technology. 32: 188–192. doi:10.1021/es9705811.


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