Cetomacrogol 1000

Cetomacrogol 1000 is the tradename for polyethylene glycol hexadecyl ether, which is nonionic surfactant produced by the ethoxylation of cetyl alcohol to give a material with the general formula HO(C₂H₄O)_nC₁₆H₃₃. Several grades of this material are available depending of the level of ethoxylation performed, with repeat units (n) of polyethylene glycol varying between 2 and 20. Commercially it can be known as Brij™ 58 (when n=20) or Brij™ 56 (when n=10). Brij™ is a trademark of Croda International.

Cetomacrogol 1000

The structure of polyethylene glycol hexadecyl ether with 20 polyethylene glycol units
Names
IUPAC name Polyethylene glycol hexadecyl ether
Other names polyoxyethylene cetyl ether Brij™ 58 Brij™ 56 Brij™ 52
Identifiers
CAS Number	9004-95-9
3D model (JSmol)	Interactive image
ChemSpider	2006409
ECHA InfoCard	100.105.524
EC Number	500-014-1
PubChem CID	2724259
CompTox Dashboard (EPA)	DTXSID60858847
InChI InChI=1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3 Key: NLMKTBGFQGKQEV-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Hazards
Safety data sheet	MSDS
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H302, H315
GHS precautionary statements	P264, P270, P280, P301+312, P302+352, P321, P330, P332+313, P362, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base. It is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.

See also

• Isoceteth-20 - a similar material made using iso-cetyl alcohol

References