Calmodulin-binding transcription activator 1

Calmodulin-binding transcription activator 1 is a protein that in humans is encoded by the CAMTA1 gene.[4][5]

CAMTA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CXK
Identifiers
Aliases	CAMTA1, CANPMR, calmodulin binding transcription activator 1
External IDs	OMIM: 611501 MGI: 2140230 HomoloGene: 18942 GeneCards: CAMTA1
Gene location (Mouse) Chr. Chromosome 4 (mouse)[1] Band 4|4 E2 Start 150,917,322 bp[1] End 151,861,876 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • sequence-specific DNA binding • DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • nucleolus • cytoplasm • cytosol Biological process • regulation of transcription, DNA-templated • neuromuscular process controlling balance • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • positive regulation of protein dephosphorylation • positive regulation of calcineurin-NFAT signaling cascade Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23261	100072
Ensembl	n/a	ENSMUSG00000014592
UniProt	Q9Y6Y1	A2A891
RefSeq (mRNA)	NM_001195563 NM_001242701 NM_015215	NM_001081557 NM_001166021 NM_001195565
RefSeq (protein)	NP_001182492 NP_001229630 NP_056030 NP_001336537 NP_001336538 NP_001336539 NP_001336541 NP_001336542 NP_001336543 NP_001336544 NP_001336545 NP_001336546 NP_001336547 NP_001336548 NP_001336549 NP_001336550 NP_001336551 NP_001336552 NP_001336553 NP_001336554 NP_001336555 NP_001336556	NP_001075026 NP_001182494
Location (UCSC)	n/a	Chr 4: 150.92 – 151.86 Mb
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCm38: Ensembl release 89: ENSMUSG00000014592 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Bouche N, Scharlat A, Snedden W, Bouchez D, Fromm H (Jun 2002). "A novel family of calmodulin-binding transcription activators in multicellular organisms". Journal of Biological Chemistry. 277 (24): 21851–61. doi:10.1074/jbc.M200268200. PMID 11925432.
5. "Entrez Gene: CAMTA1 calmodulin binding transcription activator 1".

Further reading

• Katoh M, Katoh M (2004). "Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome 1p36.31-p36.23". International Journal of Oncology. 23 (4): 1219–24. doi:10.3892/ijo.23.4.1219. PMID 12964007.
• Nakatani K, Nishioka J, Itakura T, et al. (2004). "Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells". Int. J. Oncol. 24 (6): 1407–12. doi:10.3892/ijo.24.6.1407 (inactive 2020-01-22). PMID 15138581.
• Barbashina V, Salazar P, Holland EC, et al. (2005). "Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene". Clinical Cancer Research. 11 (3): 1119–28. PMID 15709179.
• Henrich KO, Claas A, Praml C, et al. (2007). "Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma". European Journal of Cancer. 43 (3): 607–16. doi:10.1016/j.ejca.2006.09.023. PMID 17222547.
• Huentelman MJ, Papassotiropoulos A, Craig DW, et al. (2007). "Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance" (PDF). Human Molecular Genetics. 16 (12): 1469–77. doi:10.1093/hmg/ddm097. PMID 17470457.