Calfactant
Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]
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Mechanism of action
Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.[2]
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References
- "Archived copy". Archived from the original on 2011-12-09. Retrieved 2011-12-16.CS1 maint: archived copy as title (link)
- Drugs.com: Calfactant
- Schurch, S.; Lee, M.; Gehr, P. (1992). "Pulmonary surfactant: Surface properties and function of alveolar and airway surfactant". Pure and Applied Chemistry. 64 (11): 1745. doi:10.1351/pac199264111745.
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