CNOT10

CCR4-NOT transcription complex subunit 10 is a protein that in humans is encoded by the CNOT10 gene.[5] It is a subunit of the CCR4-Not deadenylase complex.

CNOT10
Identifiers
Aliases	CNOT10, CCR4-NOT transcription complex subunit 10
External IDs	MGI: 1926143 HomoloGene: 41040 GeneCards: CNOT10
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p22.3 Start 32,685,145 bp[1] End 32,773,875 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F3 Start 114,585,878 bp[2] End 114,640,184 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm • CCR4-NOT complex • cytosol • membrane • cell nucleus Biological process • nuclear-transcribed mRNA poly(A) tail shortening • gene silencing by RNA • regulation of transcription, DNA-templated • regulation of translation • transcription, DNA-templated • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • mRNA catabolic process • negative regulation of translation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25904	78893
Ensembl	ENSG00000182973	ENSMUSG00000056167
UniProt	Q9H9A5	Q8BH15
RefSeq (mRNA)	NM_001256741 NM_001256742 NM_015442	NM_153585
RefSeq (protein)	NP_001243670 NP_001243671 NP_056257	NP_705813
Location (UCSC)	Chr 3: 32.69 – 32.77 Mb	Chr 9: 114.59 – 114.64 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000182973 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000056167 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: CCR4-NOT transcription complex subunit 10". Retrieved 2020-04-15.

Further reading

• Mauxion F, Prève B, Séraphin B (February 2013). "C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex". RNA Biol. 10 (2): 267–76. doi:10.4161/rna.23065. PMC 3594285. PMID 23232451.