CLEC9A

C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene.[5]

CLEC9A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCLEC9A, DNGR1, UNQ9341, CD370, DNGR-1, C-type lectin domain family 9 member A, C-type lectin domain containing 9A
External IDsOMIM: 612252 MGI: 2444608 HomoloGene: 52106 GeneCards: CLEC9A
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12p13.2Start10,030,678 bp[1]
End10,066,031 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

283420

232414

Ensembl

ENSG00000197992

ENSMUSG00000046080

UniProt

Q6UXN8

Q8BRU4

RefSeq (mRNA)

NM_207345

NM_001205363
NM_001205364
NM_001205365
NM_172732

RefSeq (protein)

NP_997228

NP_001192292
NP_001192293
NP_001192294
NP_766320

Location (UCSC)Chr 12: 10.03 – 10.07 MbChr 6: 129.41 – 129.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[6]

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References
  1. GRCh38: Ensembl release 89: ENSG00000197992 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000046080 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: C-type lectin domain family 9 member A". Retrieved 2016-06-02.
  6. Zanders, Edward D. (2015-11-09). Human Drug Targets: A Compendium for Pharmaceutical Discovery. John Wiley & Sons. ISBN 978-1-118-84985-9.

Further reading
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human C-type lectin domain family 9 member A (CLEC9A)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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