CHTF18

Chromosome transmission fidelity protein 18 homolog is a protein that in humans is encoded by the CHTF18 gene.[5][6]

CHTF18
Identifiers
AliasesCHTF18, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL, chromosome transmission fidelity factor 18
External IDsOMIM: 613201 MGI: 2384887 HomoloGene: 32532 GeneCards: CHTF18
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p13.3Start788,046 bp[1]
End800,737 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

63922

214901

Ensembl

ENSG00000127586

ENSMUSG00000019214

UniProt

Q8WVB6

Q8BIW9

RefSeq (mRNA)

NM_022092

NM_145409

RefSeq (protein)

NP_071375

NP_663384

Location (UCSC)Chr 16: 0.79 – 0.8 MbChr 17: 25.72 – 25.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

CHTF18 has been shown to interact with:

gollark: https://www.theregister.com/2019/03/05/ai_gaydar/ (headline is vaguely misleading)
gollark: I blatantly stole it from helloboi.
gollark: I may be referred to as car/cdr if desired.
gollark: The problem with spaces is that you can’t actually see them. So you can’t be sure they’re correct. Also they aren’t actually there anyway - they are the absence of code. “Anti-code” if you will. Too many developers format their code “to make it more maintainable” (like that’s actually a thing), but they’re really just filling the document with spaces. And it’s impossible to know how spaces will effect your code, because if you can’t see them, then you can’t read them. Real code wizards know to just write one long line and pack it in tight. What’s that you say? You wrote 600 lines of code today? Well I wrote one, and it took all week, but it’s the best. And when I hand this project over to you next month I’ll have solved world peace in just 14 lines and you will be so lucky to have my code on your screen <ninja chop>.
gollark: Remove the call stack and do trampolining or something?

References
  1. GRCh38: Ensembl release 89: ENSG00000127586 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000019214 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T (Oct 2002). "A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". The Journal of Biological Chemistry. 277 (43): 40362–7. doi:10.1074/jbc.M206194200. PMID 12171929.
  6. "Entrez Gene: CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)".
  7. Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J (Sep 2003). "The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA". Proceedings of the National Academy of Sciences of the United States of America. 100 (18): 10237–42. doi:10.1073/pnas.1434308100. PMC 193545. PMID 12930902.
  8. Merkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J (Aug 2003). "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment". The Journal of Biological Chemistry. 278 (32): 30051–6. doi:10.1074/jbc.M211591200. PMID 12766176.

Further reading
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