CALN1

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.[5][6] Alternative splicing results in multiple transcript variants.[6]

CALN1
Identifiers
Aliases	CALN1, CABP8, calneuron 1
External IDs	OMIM: 607176 MGI: 2155987 HomoloGene: 10966 GeneCards: CALN1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q11.22 Start 71,779,491 bp[1] End 72,447,151 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G1.3-G2 Start 130,369,455 bp[2] End 130,847,412 bp[2]
Orthologs
Species	Human	Mouse
Entrez	83698	140904
Ensembl	ENSG00000183166	ENSMUSG00000060371
UniProt	Q9BXU9	Q9JJG7
RefSeq (mRNA)	NM_001017440 NM_031468 NM_001363460	NM_021371 NM_181045
RefSeq (protein)	NP_001017440 NP_113656 NP_001350389	NP_067346 NP_851388
Location (UCSC)	Chr 7: 71.78 – 72.45 Mb	Chr 5: 130.37 – 130.85 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.[7]

References

1. GRCh38: Ensembl release 89: ENSG00000183166 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060371 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.
6. "Entrez Gene: CALN1 calneuron 1".
7. McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.

External links

• Human CALN1 genome location and CALN1 gene details page in the UCSC Genome Browser.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–108. Nov 1998. doi:10.1101/gr.8.11.1097. PMID 9847074.