CALML3

Calmodulin-like protein 3 is a protein that in humans is encoded by the CALML3 gene.[5][6]

CALML3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GGZ
Identifiers
Aliases	CALML3, CLP, calmodulin like 3
External IDs	OMIM: 114184 MGI: 1917655 HomoloGene: 133078 GeneCards: CALML3
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p15.1 Start 5,524,961 bp[1] End 5,526,771 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A1 Start 3,802,896 bp[2] End 3,804,316 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding • GO:0001948 protein binding • calcium ion binding Cellular component • extracellular exosome • cell nucleus Biological process • calcium-mediated signaling • spindle pole body organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	810	70405
Ensembl	ENSG00000178363	ENSMUSG00000063130
UniProt	P27482	Q9D6P8
RefSeq (mRNA)	NM_005185	NM_027416
RefSeq (protein)	NP_005176	NP_081692
Location (UCSC)	Chr 10: 5.52 – 5.53 Mb	Chr 13: 3.8 – 3.8 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000178363 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000063130 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koller M, Strehler EE (May 1993). "Functional analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein". Biochim Biophys Acta. 1163 (1): 1–9. doi:10.1016/0167-4838(93)90271-R. PMID 8476923.
6. "Entrez Gene: CALML3 calmodulin-like 3".

External links

• Human CALML3 genome location and CALML3 gene details page in the UCSC Genome Browser.

Further reading

• Rhyner JA, Koller M, Durussel-Gerber I, et al. (1993). "Characterization of the human calmodulin-like protein expressed in Escherichia coli". Biochemistry. 31 (51): 12826–32. doi:10.1021/bi00166a017. PMID 1334432.
• Yaswen P, Smoll A, Peehl DM, et al. (1990). "Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 87 (19): 7360–4. doi:10.1073/pnas.87.19.7360. PMC 54746. PMID 2217169.
• Koller M, Strehler EE (1988). "Characterization of an intronless human calmodulin-like pseudogene". FEBS Lett. 239 (1): 121–8. doi:10.1016/0014-5793(88)80558-1. PMID 3181418.
• Berchtold MW, Koller M, Egli R, et al. (1993). "Localization of the intronless gene coding for calmodulin-like protein CLP to human chromosome 10p13-ter". Hum. Genet. 90 (5): 496–500. doi:10.1007/BF00217447. PMID 8428750.
• Durussel I, Rhyner JA, Strehler EE, Cox JA (1993). "Cation binding and conformation of human calmodulin-like protein". Biochemistry. 32 (23): 6089–94. doi:10.1021/bi00074a021. PMID 8507643.
• Rogers MS, Strehler EE (2001). "The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X." J. Biol. Chem. 276 (15): 12182–9. doi:10.1074/jbc.M010056200. PMID 11278607.
• Rogers MS, Kobayashi T, Pittelkow MR, Strehler EE (2001). "Human calmodulin-like protein is an epithelial-specific protein regulated during keratinocyte differentiation". Exp. Cell Res. 267 (2): 216–24. doi:10.1006/excr.2001.5254. PMID 11426940.
• Han BG, Han M, Sui H, et al. (2002). "Crystal structure of human calmodulin-like protein: insights into its functional role". FEBS Lett. 521 (1–3): 24–30. doi:10.1016/S0014-5793(02)02780-1. PMID 12067719.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Bennett RD, Mauer AS, Strehler EE (2007). "Calmodulin-like protein increases filopodia-dependent cell motility via up-regulation of myosin-10". J. Biol. Chem. 282 (5): 3205–12. doi:10.1074/jbc.M607174200. PMID 17130134.