Butyrophilin, subfamily 3, member A1

Butyrophilin subfamily 3 member A1 is a protein that in humans is encoded by the BTN3A1 gene.[3][4]

BTN3A1
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4F80, 4F9L, 4F9P, 4JKW, 4K55, 4N7I, 4N7U, 4V1P
Identifiers
Aliases	BTN3A1, BT3.1, BTF5, BTN3.1, CD277, Butyrophilin, subfamily 3, member A1, butyrophilin subfamily 3 member A1
External IDs	OMIM: 613593 HomoloGene: 56016 GeneCards: BTN3A1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.2 Start 26,402,237 bp[1] End 26,415,208 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • receptor binding Cellular component • integral component of membrane • membrane • cell membrane • external side of plasma membrane Biological process • cytokine secretion • activated T cell proliferation • T cell receptor signaling pathway • adaptive immune response • interferon-gamma secretion • immune system process • regulation of immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11119	n/a
Ensembl	ENSG00000026950	n/a
UniProt	O00481	n/a
RefSeq (mRNA)	NM_001145008 NM_001145009 NM_007048 NM_194441	n/a
RefSeq (protein)	NP_001138480 NP_001138481 NP_008979 NP_919423	n/a
Location (UCSC)	Chr 6: 26.4 – 26.42 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000026950 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Ruddy DA, Kronmal GS, Lee VK, Mintier GA, Quintana L, Domingo R Jr, Meyer NC, Irrinki A, McClelland EE, Fullan A, Mapa FA, Moore T, Thomas W, Loeb DB, Harmon C, Tsuchihashi Z, Wolff RK, Schatzman RC, Feder JN (Aug 1997). "A 1.1-Mb transcript map of the hereditary hemochromatosis locus". Genome Res. 7 (5): 441–56. doi:10.1101/gr.7.5.441. PMID 9149941.
4. "Entrez Gene: BTN3A1 butyrophilin, subfamily 3, member A1".

External links

• Human BTN3A1 genome location and BTN3A1 gene details page in the UCSC Genome Browser.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Rhodes DA, Stammers M, Malcherek G, et al. (2001). "The cluster of BTN genes in the extended major histocompatibility complex". Genomics. 71 (3): 351–62. doi:10.1006/geno.2000.6406. PMID 11170752.
• Tazi-Ahnini R, Henry J, Offer C, et al. (1998). "Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex". Immunogenetics. 47 (1): 55–63. doi:10.1007/s002510050326. PMID 9382921.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.