Butirosin

Butirosin
INN: Butirosin
	Butirosin A (top) and butirosin B (bottom)
Clinical data
Other names	Ambutyrosin; Butyrosin
Drug class	Aminoglycoside antibiotic
Identifiers
CAS Number	12772-35-9 ;
UNII	8S52KR0L58;
ChEBI	CHEBI:65109;
CompTox Dashboard (EPA)	DTXSID60925967 ;
Chemical and physical data
3D model (JSmol)	Interactive image;
	SMILES C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N;

Butirosin is an antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirocin B being the major components.[2]

References

Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.
Elks J (2014). The Dictionary of Drugs. Springer. p. 198.

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[Heifetz-1] Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.

[2] Elks J (2014). The Dictionary of Drugs. Springer. p. 198.