Bicine

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C.[1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.[2]

Bicine

Names
IUPAC name 2-(Bis(2-hydroxyethyl)amino)acetic acid
Other names N,N-Bis(2-hydroxyethyl)glycine; Diethylolglycine; Diethanol glycine; Dihydroxyethylglycine; BHG
Identifiers
CAS Number	150-25-4^Y
3D model (JSmol)	Interactive image
Abbreviations	DHEG
ChEBI	CHEBI:39066^Y
ChEMBL	ChEMBL1231251^N
ChemSpider	8431^Y
DrugBank	DB03709^Y
ECHA InfoCard	100.005.233
PubChem CID	8761
UNII	1J484QFI1O^Y
CompTox Dashboard (EPA)	DTXSID3041669
InChI InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)^Y Key: FSVCELGFZIQNCK-UHFFFAOYSA-N^Y InChI=1/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Key: FSVCELGFZIQNCK-UHFFFAOYAV
SMILES O=C(O)CN(CCO)CCO
Properties
Chemical formula	C6H13NO4
Molar mass	163.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O₂, SO₂, H₂S or Thiosulfate.[3]

See also

• Tricine

References

1. N,N-Bis(2-hydroxyethyl)glycine at ChEBI
2. The Merck Index (10th ed.). Rahway, NJ: Merck & Co. 1983. p. 453. ISBN 0-911910-27-1.
3. Lawson, Gary (2003). "Amine Plant Corrosion Reduced by Removal of Bicine" (PDF). Gas Processors Association Annual Convention. Archived from the original (PDF) on 2015-06-16. Retrieved March 2016. Check date values in: |access-date= (help)