Bat influenza

Bat influenza is a type of influenza A viruses found in bats.[1] Bats were not considered to host Influenza A viruses until 2012-2013, when two phylogenetically distinct lineages, designated Influenza A virus subtype H17N10 and H18N11, were identified in Central and South American bats.

Discovery

The species of bats currently known to carry bat influenza are common in Central and South America.[1] The first bat flu virus, IAV H17N10, was first discovered in 2009 in little yellow-shouldered bats (Sturnira lilium) in Guatemala.[1] In 2012 a novel influenza virus (H18N11) was discovered in bats in South America. This strain was found to be divergent from the better-understood Influenza A viruses most commonly found in fowls and humans.[2] The complete sequence of IAV H17N10 was extracted from Sturnira lilium in 2012. In 2013, the sequence of IAV H18N11 was extracted from flat-faced fruit-eating bats (Artibeus planirostris) from Peru.[3][4][5]

Other species

Influenza A viruses circulate among a wide variety of species, being able to cross species barriers and establish new virus lineages in birds and mammals.[5] However, bat influenza viruses have been found to be poorly adapted to non-bat species.[6]

Infection in humans

As of 2019, no cases of influenza in humans have been definitively linked to bats.[7] Research suggests that human cells do not support growth of bat flu viruses in the test tube, implying that these viruses would need to undergo significant changes to adapt and easily infect humans. However, a transmission potential has been found, but the mechanism of transmission from bats to humans differs from that from other species.[7] It has been argued that bat flu viruses could become capable of infecting humans by exchanging genetic information with human flu viruses through reassortment.[1]

References
  1. "Bat Influenza (Flu)". cdc.gov. Retrieved 30 June 2020.
  2. "Turns Out, Bat Influenza Can Give You the Flu". globalbiodefense.com. Retrieved 27 June 2020.
  3. "Characterization of bat influenza viruses". uniklinik-freiburg.de. Retrieved 30 June 2020.
  4. "New flu virus found in bats". nature.com. Retrieved 30 June 2020.
  5. Ciminski, Kevin; Pfaff, Florian; Beer, Martin; Schwemmle, Martin. "Bats reveal the true power of influenza A virus adaptability". doi:10.1371/journal.ppat.1008384. Cite journal requires |journal= (help)
  6. Ciminski, Kevin; Gorka, Marco; Lee, Jinhwa; Malmlov, Ashley; Schinköthe, Jan; Eckley, Miles; Murrieta, Reyes A; Aboellail, Tawfik A; Campbell, Corey L; Ebel, Gregory D; Ma, Jingjiao; Pohlmann, Anne; Franzke, Kati; Ulrich, Reiner; Hoffmann, Donata; García-Sastre, Adolfo; Ma, Wenjun; Schountz, Tony; Beer, Martin; Ran, Wei; Schwemmle, Martin. "Bat Influenza Viruses Transmit Among Bats but Are Poorly Adapted to Non-Bat Species". doi:10.1038/s41564-019-0556-9. PMID 31527796. Cite journal requires |journal= (help)
  7. "Study Identifies Transmission Mechanism of Bat Influenza". contagionlive.com. Retrieved 27 June 2020.
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