BNIPL

Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein is a protein that in humans is encoded by the BNIPL gene.[5][6][7]

BNIPL
Identifiers
AliasesBNIPL, BNIP-S, BNIPL-1, BNIPL-2, BNIPL1, BNIPL2, BNIPS, PP753, BCL2/adenovirus E1B 19kD interacting protein like, BNIP-Salpha, BNIP-Sbeta, BCL2 interacting protein like
External IDsOMIM: 611275 MGI: 2384749 HomoloGene: 15900 GeneCards: BNIPL
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q21.3Start151,036,321 bp[1]
End151,047,720 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

149428

171388

Ensembl

ENSG00000163141

ENSMUSG00000028115

UniProt

Q7Z465

Q99JU7

RefSeq (mRNA)

NM_001159642
NM_138278
NM_138279

NM_001168356
NM_134253

RefSeq (protein)

NP_001153114
NP_612122

NP_001161828
NP_599014

Location (UCSC)Chr 1: 151.04 – 151.05 MbChr 3: 95.24 – 95.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

BNIPL has been shown to interact with:

gollark: For all the "instability" of Arch, it doesn't randomly do that.
gollark: Is anything below `ghc` in the stack implementation details to you?
gollark: The machine code for them is excessively complex too, now, but I suppose you mostly write Haskell and whatnot which is then compiled to that.
gollark: They have ridiculously complex manufacturing processes because the transistors are on the scale of a few hundred atoms, it's crazy.
gollark: Also, with your processor comment, you are kind of underselling the complexity involved. It's not separate transistors, they're all just made on large bits of silicon together and wired up. Billions of them per processor.

References
  1. GRCh38: Ensembl release 89: ENSG00000163141 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028115 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Shen L, Hu J, Lu H, Wu M, Qin W, Wan D, Li YY, Gu J (Apr 2003). "The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER". FEBS Letters. 540 (1–3): 86–90. doi:10.1016/S0014-5793(03)00229-1. PMID 12681488.
  6. Zhou YT, Soh UJ, Shang X, Guy GR, Low BC (Mar 2002). "The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence". The Journal of Biological Chemistry. 277 (9): 7483–92. doi:10.1074/jbc.M109459200. PMID 11741952.
  7. "Entrez Gene: BNIPL BCL2/adenovirus E1B 19kD interacting protein like".
  8. Qin W, Hu J, Guo M, Xu J, Li J, Yao G, Zhou X, Jiang H, Zhang P, Shen L, Wan D, Gu J (Aug 2003). "BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis". Biochemical and Biophysical Research Communications. 308 (2): 379–85. doi:10.1016/s0006-291x(03)01387-1. PMID 12901880.
  9. Yasuda M, Han JW, Dionne CA, Boyd JM, Chinnadurai G (Feb 1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Research. 59 (3): 533–7. PMID 9973195.

Further reading


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