BAZ2A

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene.[5][6][7]

BAZ2A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4LZ2, 4Q6F, 4QBM, 4QF2, 5AGQ
Identifiers
Aliases	BAZ2A, TIP5, WALp3, bromodomain adjacent to zinc finger domain 2A
External IDs	OMIM: 605682 MGI: 2151152 HomoloGene: 8393 GeneCards: BAZ2A
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.3 Start 56,595,596 bp[1] End 56,636,816 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 128,091,577 bp[2] End 128,129,303 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • GO:0001187 RNA polymerase I core promoter sequence-specific DNA binding • histone binding • metal ion binding • GO:0001948 protein binding • ligand-dependent nuclear receptor binding • lysine-acetylated histone binding • RNA binding Cellular component • rDNA heterochromatin • chromatin silencing complex • nucleolus • cell nucleus • cytosol • nuclear speck Biological process • chromatin remodeling • regulation of transcription, DNA-templated • transcription, DNA-templated • DNA methylation • chromatin silencing at rDNA • histone deacetylation • RNA polymerase I transcriptional preinitiation complex assembly • chromatin organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11176	116848
Ensembl	ENSG00000076108	ENSMUSG00000040054
UniProt	Q9UIF9	Q91YE5
RefSeq (mRNA)	NM_001300905 NM_013449 NM_001351156	NM_054078
RefSeq (protein)	NP_001287834 NP_038477 NP_001338085	n/a
Location (UCSC)	Chr 12: 56.6 – 56.64 Mb	Chr 10: 128.09 – 128.13 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000076108 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040054 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jones MH, Hamana N, Nezu Ji, Shimane M (Jan 2000). "A novel family of bromodomain genes". Genomics. 63 (1): 40–5. doi:10.1006/geno.1999.6071. PMID 10662543.
6. Strohner R, Nemeth A, Jansa P, Hofmann-Rohrer U, Santoro R, Längst G, Grummt I (Sep 2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines". The EMBO Journal. 20 (17): 4892–900. doi:10.1093/emboj/20.17.4892. PMC 125270. PMID 11532953.
7. "Entrez Gene: BAZ2A bromodomain adjacent to zinc finger domain, 2A".

External links

• Human BAZ2A genome location and BAZ2A gene details page in the UCSC Genome Browser.

Further reading

• Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
• Zhou Y, Santoro R, Grummt I (Sep 2002). "The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription". The EMBO Journal. 21 (17): 4632–40. doi:10.1093/emboj/cdf460. PMC 126197. PMID 12198165.
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M (2007). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biology. 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMC 2374985. PMID 17672918.