BAIAP2L1

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 is a protein that in humans is encoded by the BAIAP2L1 gene.[5]

BAIAP2L1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KXC, 2LNH
Identifiers
Aliases	BAIAP2L1, IRTKS, BAI1 associated protein 2 like 1, BAR/IMD domain containing adaptor protein 2 like 1
External IDs	OMIM: 611877 MGI: 1914148 HomoloGene: 23123 GeneCards: BAIAP2L1
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.3-q22.1 Start 98,291,650 bp[1] End 98,401,090 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 144,264,526 bp[2] End 144,358,112 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • actin binding • proline-rich region binding • GO:0001948 protein binding • cadherin binding involved in cell-cell adhesion Cellular component • cytosol • cell membrane • extracellular exosome • cytoskeleton • nucleoplasm • actin cytoskeleton • cytoplasm Biological process • insulin receptor signaling pathway • regulation of actin filament polymerization • plasma membrane organization • positive regulation of actin cytoskeleton reorganization • positive regulation of actin filament polymerization • response to bacterium • regulation of insulin receptor signaling pathway • actin filament bundle assembly • actin crosslink formation • cell-cell adhesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55971	66898
Ensembl	ENSG00000006453	ENSMUSG00000038859
UniProt	Q9UHR4	Q9DBJ3
RefSeq (mRNA)	NM_018842	NM_025833
RefSeq (protein)	NP_061330	NP_080109
Location (UCSC)	Chr 7: 98.29 – 98.4 Mb	Chr 5: 144.26 – 144.36 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000006453 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038859 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: BAIAP2L1 BAI1-associated protein 2-like 1".

Further reading

• Millard TH, Dawson J, Machesky LM (2007). "Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties". J. Cell Sci. 120 (Pt 9): 1663–72. doi:10.1242/jcs.001776. PMID 17430976.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.

External links

• Human BAIAP2L1 genome location and BAIAP2L1 gene details page in the UCSC Genome Browser.