Angiomatoid fibrous histiocytoma

Angiomatoid fibrous histiocytoma, abbreviated AFH, is a rarely metastasizing tumour that affects children and young adults.

Angiomatoid fibrous histiocytoma
Micrograph showing a angiomatoid fibrous histiocytoma. H&E stain.

Pathology

It is characterized cystic blood-filled spaces and composed of histiocyte-like cells. A lymphocytic cuff is common. It often simulates a vascular lesion, and was initially described as doing this.[1]

AFH typically has a chromosomal translocation involving the ATF1 gene -- t(12;16) FUS/ATF1 or t(12;22) EWS/ATF1.

Diagnosis

Treatment
gollark: You could configure the Linuxuous apioids to run the CPU at minimum clock.
gollark: I was going to get one of those, but then I realized that my Raspberry Pi 3 was utterly underutilized and I would never use it.
gollark: A fabless SoC designer.
gollark: ?
gollark: You mostly just lose out on any usable IO.

See also

References
  1. Enzinger, FM. (Dec 1979). "Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm". Cancer. 44 (6): 2147–57. doi:10.1002/1097-0142(197912)44:6<2147::aid-cncr2820440627>3.0.co;2-8. PMID 228836.
Classification
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.